Reference 66

Level I Good quality evidence Systematic review of RCTs with

consistent findings
High quality individual RCT
Level II Limited quality patient

orientated evidence
Systematic review of lower
quality
studies or studies with inconsistent
findings
Low quality clinical trial
Cohort studies
Case-control studies
Level III
Other
Consensus
guidelines, extrapolations
from bench research, usual practice,
opinion, disease-oriented evidence
(intermediate or physiologic outcomes
only), or case series

[66] Monitoring and management of viral loads (children): 2019 ART Clinical Guidelines for the Management of HIV in Adults, Pregnancy, Adolescents, Children, Infants and Neonates. https://www.knowledgehub.org.za/elibrary/2019-art-clinical-guidelines-management-hiv-adults-pregnancy-adolescents-children-infants

Monitoring and management of viral loads (children): National Department of Health, Essential Drugs Programme: Paediatric Hospital Level STGs and EML, 2020 (draft). http://www.health.gov.za/