| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[2] Immediate initiation of ART, pregnant and breastfeeding women: National Department of Health.National consolidated guidelines for the prevention of mother-to-child transmission of HIV (PMTCT) and the management of HIV in children, adolescents and adults, 2014.http://www.health.gov.za/
Immediate initiation of ART, pregnant and breastfeeding women: WHO. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection, June 2013.Web annexes: Chapter 7 Clinical guidance across the continuum of care: antiretroviral therapy guidelines;Section 7.1.2: When to start ART in pregnant and breastfeeding women and GRADE tables.http://www.who.int/hiv/pub/guidelines/arv2013/annexes/en/index2.html