Reference 8

Level I Good quality evidence Systematic review of RCTs with
consistent findings
High quality individual RCT
Level II Limited quality patient
orientated evidence
Systematic review of lower quality
studies or studies with inconsistent
findings
Low quality clinical trial
Cohort studies
Case-control studies
Level III Other Consensus guidelines, extrapolations
from bench research, usual practice,
opinion, disease-oriented evidence
(intermediate or physiologic outcomes
only), or case series

[8] Levnorgestrel IUD: National Department of Health: Affordable Medicines, EDP- Primary Healthcare level. Medicine Review: Levonorgestrel-releasing intrauterine system for contraception, April 2013. https://www.knowledgehub.org.za/e-library

Levnorgestrel IUD: National Department of Health: Affordable Medicines, EDP- Primary Healthcare level. Medicine Review: Low-dose levonorgestrel-releasing intrauterine system for contraception, August 2020. https://www.knowledgehub.org.za/e-library

Levnorgestrel IUD: World Health Organization Department of Reproductive Health and Research (WHO/RHR) and Johns Hopkins Bloomberg School of Public Health/Center for Communication Programs (CCP), Knowledge for Health Project. Family Planning: A Global Handbook for Providers (2018 update). Baltimore and Geneva: CCP and WHO, 2018. https://www.who.int/reproductivehealth/publications/fp-global-handbook/en/