Injectable

Z30.0/Z30.4

Dual protection with barrier methods is recommended to reduce the risk of STIs, including HIV.

  • Progestin-only injectable contraceptive, e.g.:
    • Medroxyprogesterone (long-acting), IM, 150 mg, 12 weekly. LoEI[12]

Progestin-only hormonal contraceptives are contraindicated in certain conditions e.g. unexplained vaginal bleeding. Consult the package insert in this regard.

When to start the injection

  • The injection can be started anytime within the menstrual cycle, provided pregnancy has been excluded. If the first injection is given within 7 days of the onset of the menstrual cycle, the contraceptive effect is achieved on the day of the first injection.
  • If started after day 7,advise the woman to abstain from intercourse or use condoms for the next 7 days.
  • Can be used postpartum.

LoE:III[13]

Late injection

  • If it has been <2 weeks since the missed injection, the next injection can be given without loss of protection. Continue with dual contraceptive method, i.e. condom in combination with the injection.
  • If it has been >2 weeks since the missed injection, exclude pregnancy:

Pregnancy test positive Pregnancy test
negative or unavailable
»     Refer for ante-natal care
(See Section 6.4: Antenatal care).
or
»     TOP, see:
Termination of pregnancy (TOP).
»     Provide emergency
contraception, if indicated (see: Contraception, emergency).
»     Administer the next injection.
»     Advise the woman to abstain
from intercourse or use condoms to prevent pregnancy for the next 7 days.
Pregnancy test positive Pregnancy test
negative or unavailable

See: Termination of pregnancy (TOP).

See: Contraception, emergency

LoEIII[14]

There is uncertainty of the risk of HIV acquisition associated with progestin injectable contraceptives (Refer to the WHO MEC 2017 guidelines[¹⁵]). Dual protection is recommended.

REFERRAL

Heavy or prolonged bleeding, despite adequate treatment with combined oral contraceptives. See: Breakthrough bleeding with contraceptive use.