| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[1] Lidocaine: National Department of Health. Government Gazette: No. 36827: Medicines and related substances Act, 1965; Schedules (Regulation674), 13 September 2013. http://www.sabinetlaw.co.za/health
Lidocaine with epinephrine (adrenaline): National Department of Health. Government Gazette: No. 36827: Medicines and related substances Act, 1965; Schedules (Regulation674), 13 September 2013. http://www.sabinetlaw.co.za/health