Reference 12

Level I Good quality evidence Systematic review of RCTs with
consistent findings
High quality individual RCT
Level II Limited quality patient
orientated evidence
Systematic review of lower quality
studies or studies with inconsistent
findings
Low quality clinical trial
Cohort studies
Case-control studies
Level III Other Consensus guidelines, extrapolations
from bench research, usual practice,
opinion, disease-oriented evidence
(intermediate or physiologic outcomes
only), or case series

[12] Glycopyrrolate: Kongsgrud F, Sponheim S. A Comparison of Atropine and Glycopyrrolate in Anaesthetics Practice. Acta Anaesth Scand. 1982. 25 (5): 620-625. AND Salem MG, Richardson JC, Meadows GA, Lampluch G, Lai KM. Comparison between glycopyrrolate and atropine in a mixture with neostigmine for reversal of neuromuscular blockage: Studies in patients following open heart surgery. BJA. 1985, 57(2): 184-187.