Abbreviations

  • 3TC lamivudine
  • ABC abacavir
  • ACTH adrenocorticoid hormone
  • ADA adenosine deaminase
  • ADEM acute disseminated encephalomyelitis
  • ADH antidiuretic hormone
  • ADHD attention deficit hyperactivity disorder
  • ADR adverse drug reaction
  • AED antiepileptic drug
  • AFP acute flaccid paralysis
  • AI aortic incompetence
  • AIDP acute inflammatory demyelinating polyradiculoneuropathy
  • AIDS acquired immune deficiency syndrome
  • ALP alkaline phosphatase
  • ALT alanine aminotransferase
  • AMAN acute motor axonal neuropathy
  • AMSAN acute motor-sensory axonal neuropathy
  • ANA anti-nuclear antibody
  • AP anteroposterior
  • APH antepartum haemorrahge
  • APSGN acute poststreptococcal glomerulonephritis
  • ARDS acute respiratory distress syndrome
  • ART antiretroviral therapy
  • ARV antiretroviral
  • ASA American Society of Anaesthesiology
  • ASD atrial septal defect
  • ASO antistreptolysin O
  • ASOT antistreptolysin O titre
  • AST aspartate aminotransferase
  • AVSD atrioventricular septal defect
  • AZT zidovudine
  • BCG Bacille Calmette-Guérin
  • BD twice daily
  • BHCG beta-human chorionic gonadotropin
  • BIPP bismuth iodoform paraffin paste
  • BMI body mass index
  • BP blood pressure
  • BSA body surface area
  • CA-MRSA community aquired methicillin-resistant Staphylococcus aureus
  • cART combination antiretroviral therapy
  • CBT cognitive behavioural therapy
  • CD4 cluster of differentiation 4
  • CDC Centers for Disease Control and Prevention
  • CHD congenital heart disease
  • CIDP chronic inflammatory demyelinating polyradiculoneuropathy
  • CKD chronic kidney disease
  • CMP comprehensive metabolic panel
  • CMV cytomegalovirus
  • CNS central nervous system
  • COCs combined oral contraceptives
  • CPAP continuous positive airway pressure
  • CPP cerebral perfusion pressure
  • CPR cardiopulmonary resuscitation
  • CRF chronic renal failure
  • CRP C-Reactive Protein
  • CRT capillary refilling time
  • CSF cerebrospinal fluid
  • CT computerized tomography
  • CVP central venous pressure
  • CVT cerebral venous thrombosis
  • d4T stavudine
  • DAT diphtheria antitoxin treatment
  • DC direct current
  • DEET diethyltoluamide
  • DIC disseminated intravascular coagulation
  • DKA diabetic ketoacidosis
  • dL decilitre
  • DMARDs disease modifying antirheumatic drugs
  • DMDD disruptive mood dysregulation disorder
  • DNA deoxyribonucleic acid
  • DOT directly observed therapy
  • DPT diphtheria, pertussis, tetanus
  • DR drug resistance
  • DRESS drug-induced rash with eosinophilia and systemic symptoms
  • DSD disorders of sexual development
  • DSM diagnostic and statistical manual
  • DST drug susceptibility testing
  • E ethambutol
  • ECG electrocardiogram
  • eCrCl estimated creatinine clearance
  • EEG electroencephalogram
  • EFV efavirenz
  • ELISA enzyme linked immunosorbent assay
  • EMB ethambutol
  • ENT ear, nose and throat
  • EPI expanded programme on immunisation
  • ESPE extrapyramidal side effects
  • ESPGHAN European Society for Paediatric Gastroenterology Hepatology and Nutrition
  • ESR erythrocyte sedimentation rate
  • ESRF end stage renal failure
  • ETAT emergency triage assessment and treatment
  • ETT endotracheal tube
  • FBC full blood count
  • FDA Food and Drug Administration
  • FDC fixed dose combination
  • FDP freeze dried plasma
  • FEV forced expiratory volume
  • FEV1 forced expiratory volume in 1 second
  • FFP fresh frozen plasma
  • FiO2 fraction of inspired oxygen
  • FLACC face, legs, activity, cry, consolability
  • FSGS focal segmental glomerulosclerosis
  • g gram
  • G6PD glucose-6-phosphate dehydrogenase
  • GABA gamma aminobutyric acid
  • GAD generalised anxiety disorder
  • GBS Guillain-Barre' syndrome
  • GCS glasgow coma scale
  • GEFS+ genetic epilepsy with febrile seizures plus
  • GFR glomerular filtration rate
  • GGT gamma-glutamyl transferase
  • GIT gastrointestinal tract
  • GMP Good Manufacturing Practice
  • GORD gastro-oesophageal reflux disease
  • GTCS generalised tonic-clonic seizures
  • H isoniazid
  • Hb haemoglobin
  • HbA1C glycosylated haemoglobin, type A1C
  • HBV hepatitis B virus
  • HCV hepatitis C virus
  • HCV head circumference
  • Hib haemophilus influenza type B
  • HIE hypoxic-ischaemic encephalopathy
  • HIV human immunodeficiency virus
  • HLA human leukocyte antigen
  • HMD hyaline membrane disease
  • HSP Henoch-Schönlein purpura
  • HSV herpes simplex virus
  • HT hypertension
  • IAS intra-articular steroids
  • ICHD International Classification of Headache Disorders
  • ICP intracranial pressure
  • ICU intensive care unit
  • IE infective endocarditis
  • IgE Immunoglobulin E
  • IgG immunoglobulin G
  • IgM immunoglobulin M
  • ILAE International League against Epilepsy
  • IM intramuscular
  • IMCI Integrated Management of Childhood Illness
  • IMI intramuscular injection
  • INH isoniazid
  • INR international normalised ratio
  • IO intraosseous
  • IPT isoniazid prevention therapy
  • IRDS infant respiratory distress syndrome
  • IRIS immune reconstitution inflammatory syndrome
  • ITP immune thrombocytopaenic purpura
  • IU international unit
  • IUCDs intra-uterine contraceptive device
  • IV intravenous
  • J joule
  • JIA juvenile idiopathic arthritis
  • JVP jugular venous pressure
  • KDQOI Kidney Disease Outcomes Quality Initiative
  • kg kilogram
  • kJ kilojoule
  • L litre
  • LABA long-acting beta agonist
  • LDH lactate dehydrogenase
  • LDL low-density lipoprotein
  • LDL-C low-density-lipoprotein cholesterol
  • LFTs liver function tests
  • LGE lineal gingival erythema
  • LGS Lennox-Gastaut syndrome
  • LIP lymphoid interstitial pneumonitis
  • LMWH low molecular weight heparin
  • LOC loss of consciousness
  • LoE level of evidence
  • LP lumbar puncture
  • LPV/r lopinavir/ritonavir
  • LTB laryngotracheobronchitis
  • MAC mycobacterium avium complex
  • MAS meconium aspiration syndrome
  • MCNS minimal change nephrotic syndrome
  • MCS microscopy, culture, sensitivity
  • MCUG micturating cystourethrogram
  • MCV meningococcal conjugate vaccine
  • MDD major depressive disorder
  • MDI metered-dose inhaler
  • MDR multi-drug resistant
  • mg milligram
  • MI mitral incompetence
  • mL millilitre
  • mmol millimole
  • MRI magnetic resonance imaging
  • MRSA methicillin-resistant Staphylococcus aureus
  • MTB mycobacterium tuberculosis
  • NAC N-acetyl cysteine
  • NAS neonatal abstinence syndrome
  • NEC necrotising enterocolitis
  • NGAs nasogastric aspirates
  • NGT nasogastric tube
  • NHLS National Health Laboratory Service
  • NICD National Institute for Communicable Diseases
  • NIMART nurse-initiated and managed antiretroviral therapy
  • NMS neuroleptic malignant syndrome
  • NNRTIs non-nucleoside reverse transcriptase inhibitors
  • NNT number needed to treat
  • NRTIs nucleoside reverse transcriptase inhibitors
  • NS nephrotic syndrome
  • NSAIDs nonsteroidal antiinflammatory drugs
  • NTS non-typhoid salmonella
  • NVP nevirapine
  • OCD obsessive compulsive disorder
  • ODD oppositional defiant disorder
  • OME otitis media with effusion
  • ORS oral rehydration solution
  • PA posteroanterior
  • PA pulmonary atresia
  • PaCO₂ partial pressures of carbon dioxide
  • PAIR percutaneous puncture aspiration injection
  • PANDAS paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections
  • PCR polymerase chain reaction
  • PCV pneumococcus conjugate vaccine
  • PDA patent duct arteriosus
  • PEA pulseless electrical activity
  • PEF peak expiratory flow
  • PEFR peak expiratory flow rate
  • PGL persistent generalised lymphadenopathy
  • PHC primary healthcare
  • PI protease inhibitor
  • PJP pneumocystis jiroveci pneumonia
  • PML progressive multifocal leukoencephalopathy
  • PMTCT prevention of mother to child transmission
  • PN parenteral nutrition
  • PPHN persistent pulmonary hypertension of the newborn
  • PPN partial parenteral nutrition
  • PPV pneumococcus polysaccaride vaccine
  • PT prothrombin time
  • PTB pulmonary tuberculosis
  • PTSD post traumatic stress disorder
  • PTT partial thromboplastin time
  • PZA pyrazinamide
  • R rifampicin
  • RBC red blood cell
  • RF rheumatoid factor
  • rHuEPO recombinant human erythropoietin
  • RIG rabies immunoglobulin
  • RNA nribonucleic acid
  • ROP retinopathy of prematurity
  • RPR rapid plasma reagin
  • RSTI repeated supratherapeutic ingestion
  • SAM severe acute malnutrition
  • SANCA South African National Council on Alcoholism and Drug Dependence
  • SaO₂ Oxygen saturation
  • SC subcutaneous
  • SD standard deviation
  • SE status epilepticus
  • SIADH syndrome ofinappropriate antidiuretic hormone secretion
  • SIDS sudden infant death syndrome
  • SJS Stevens-Johnson Syndrome
  • SLE systemic lupus erythematosus
  • SMEI severe myoclonic epilepsy of infancy
  • SAHPRA South African Health Products Regulatory Authority
  • SSRI selective serotonin re-uptake inhibitors
  • SSS sugar and salt solution
  • STI sexually transmitted infection
  • SUD substance use disorders
  • TA tricuspid atresia
  • TB tuberculosis
  • TB tuberculous meningitis
  • TC total cholesterol
  • TCA tricyclic antidepressants
  • Td tenus, diphtheria
  • TDF tenofovir
  • TEN toxic epidermal necrosis
  • TG triglycerides
  • TGA transposition of great arteries
  • TIG tetanus immunoglobulin
  • TOF tetralogy of fallot
  • TPN total parenteral nutrition
  • TSH thyroid-stimulating hormone
  • TST tuberculin skin test
  • TT tetanus toxoid
  • TTN transient tachypnoea of the newborn
  • U&E urea and electrolytes
  • UCT University of Cape Town
  • UFH unfractioned heparin
  • URTI upper respiratory tract infection
  • UTI urinary tract infection
  • VL viral load
  • VLDL very low-density lipoprotein
  • VP ventriculoperitoneal
  • VSD ventricular septal defect
  • WHO World Health Organisation
  • Wt - weight
  • XDR extensively drug-resistant
  • Z pyrazinamide